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Joseph W. Hegeman was a son of Joseph Hegeman, a wealthy gentleman who lived at Coenties slip in New York. Joseph was born and educated at Princeton, New Jersey, and there received his license to practice medicine. He was a friend of Dr. William Anderson, and removed with him to Schenectady where he was associated with him as a partner in business. He was a man of gentlemanly and courteous manners, and was esteemed a good practitioner. He married Sophia Anderson, a sister of his friend and partner, Dr. Anderson. About 1814 he removed to Cincinnati, and in 1827 to Vicksburgh, Mississippi, where he continued in practice with a relative of his wife. In 1832 he lost his three daughters, who died of cholera within twelve hours of each other. He died in 1837. The date of his birth is uncertain, but he was not far from sixty-five years of age at the time of his decease.